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研究業績

英文論文

2020年

  • Jinnouchi O, Ohnishi H, Kondo E, Kawata I, Bando H, Okamoto H, Azuma T, Sato G, Kitamura Y, Abe K, Takeda N.
    Aural stimulation with capsaicin prevented pneumonia in dementia patients.
    Auris Nasus Larynx 47: 154-157, 2020.

2019年

  • Matsuda K, Kitahara T, Ito T, Fukushima M, Fukuda J, Sato G, Kitamura Y, Abe K, Uno A, Tomita K, Sakata-Haga H, Fukui Y, Takeda N.
    A new immunohistochemical method to evaluate the development of vestibular compensation after unilateral labyrinthectomy in rats..
    Acta Otolaryngol. 139: 505-510, 2019.
  • Sato G, Matsuda K, Matsuoka M, Fukuda J, Morita Y, Takahashi K, Horii A, Takeda N.
    Comparative study of anti-vertiginous and anti-anxious drugs for the treatment of chronic vestibular patients with secondary anxiety.
    Acta Oto-Laryngologica. 139: 593-597, 2019.
  • Fijimoto C, Tamura K, Takaishi S, Kawata I, Kitamura Y, Takeda N.
    Short-term pre-operative systemic administration with low-dose of steroid dose not make a false-negative diagnosis of definite eosinophilic chronic rhinosinusitis affet endoscopic sinus surgery.
    J. Med. Invest. 66: 233-236, 2019.
  • Fukushima M, Oya R, Nozaki K, Eguchi H, Akahani S, Inohara H, Takeda N.
    Vertical head impulse and caloric are complementary, but react opposite to endolymphatic hydrops in Meniere’s disease.
    Laryngoscope 129: 1660-1666, 2019.
  • Fukushima M, Akahani S, Inohara H, Takeda N.
    Endolymphatic hydrops of Meniere’s disease shown by 3-Tesla MRI is stable during and after vertigo attacks.
    JAMA Otolaryngol. Head Neck Surg. 145: 583-585, 2019.
  • Imai T, Okumura T, Sato T, Takeda N, Ohta Y, OkazakiS, Inohara H.
    Effects of interval time of the Epley maneuver on immediate reduction of positional nystagmus: a randomized, controlled, nonblinded clinical trial.
    Front. Neurol. 10: 304, 2019.
  • Ito T, Inui H, Miyasaka T, Sakamoto T, Shiozaki T, Matsuyama S, Yamanaka T, Kichikawa K, Takeda N, Kitahara T.
    Three-dimensional magnetic resonance imaging reveals the relationship between the control of vertigo and decreases in endolymphatic hydrops after endolymphatic sac drainage with steroids for Meniere’s disease.
    Front. Neurol. 10: 36, 2019.

2018年

  • Martin H, Go S, Yan-Feng Z, Stephane B, Paul F. S.
    Effects of electrical stimulation of the rat vestubular labyrinth on c-Fos expression in the hippocampus.
    Neurosci. Lett. 677: 60-64, 2018.
  • Azuma T, Nogaki T, Schachern P, Paparella M.M, Cureoglu S.
    Structural Analysis of Tensor Tympani Muscle, Tympanic Diaphragm, Epitympanum, and Protympanum in Menière's Disease: a Human Temporal Bone Study.
    Otol. Neurotol. 39: 499-505, 2018.
  • Shimada A, Udaka J, Nagashima H, Chida I, Kondo E, Nakano S, Okamoto H, Takeda N.
    Effects of FM system fitted into normal hearing ear on speech-in-noise recognition in Japanese school-aged children with unilateral severe-to-profound hearing loss.
    J. Med. Invest. 65: 216-220, 2018.
  • Azuma T, Nakamura K, Takahashi M, Miyoshi H, Toda N,  Iwasaki H, Takeda N.
    Electroneurography in the acute stage of facial palsy as a predictive factor for the development of facial synkinesis sequela.
    Auris Nasus Larynx. 45: 728-731, 2018.
  • Fujii T, Kitamura Y, Mizuguchi H, Okamoto K, Sanada N, Yamada T, Sugiyama M, Michinaga S, Kitayama M, Fukui H, Takeda N.
    Effects of irradiation with narrowband-ultraviolet B on up-regulation of histamine H1 receptor mRNA and induction of apoptosis in HeLa cells and nasal mucosa of rats.
    J. Pharmacol. Sci. 138: 54-62, 2018.
  • Islam R, Mizuguchi H, Shaha A, Nishida K, Yabumoto M, Ikeda H, Fujino H, Kitamura Y, Fukui H, Takeda N.
    Effect of wild grape on the signaling of histamine H1 receptor gene expression responsible for the pathogenesis of allergic rhinitis.
    J. Med. Invest. 65: 242-250, 2018.
  • Martin H, Go S, Yan-Feng Z, Stephane B, Paul F. S
    Vestibular-related eye movements in the rat following selective electrical stimulation of the vestibular sensors.
    J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. 204: 835-847, 2018.
  • Shaha A, Mizuguchi H, Kitamura Y, Fujino H, Yabumoto M, Takeda N, Fukui H.
    Effect of Royal jelly and Brazilian green propolis on the signaling for histamine H1 receptor and interleukin-9 gene expressions responsible for the pathogenesis of the allergic rhinitis.
    Biol. Pharm. Bull. 41: 1440-1447, 2018.
  • Nogaki T, Keskin N, Azuma T, Paparella M.M , Nadol J. B, Cureoglu S.
    Quantitative assessment of vestibular otopathology in granulomatosis with polyangitis: a temporal bone study.
    Laryngoscope Investig. Otolaryngol. 3: 473-477, 2018.
  • Imai T, Okumura T, Nishiike S, Takeda N, Ohta Y, Osaki Y, Sato T, Inohara H.
    Recovery of positional nystagmus after benign paroxysmal positional vertigo fatigue.
    Eur. Arch. Otolaryngol. 275: 2967-2973, 2018.
  • Imai T, Takimoto Y, Okumura T, Higashi-Shingai K, Takeda N, Kitamura K, Kalubi B, Fujikado T, Hirota M, Midoh Y, Nakamae K, Inohara H.
    Visual target strategies in infantile nystagmus patients with horizontal jerk waveform.
    Front. Neurol. 9: 622, 2018.  

2017年

  • Okazaki S, Imai T, Higashi-Shingai K, Matsuda K, Takeda N, Kitahara T, Uno A, Horii A, Ohta Y, Morihana T, Masumura C, Nishiike S, Inohara H.
    Office-based differential diagnosis of transient and persistent geotropic positional nystagmus in patients with horizontal canal type of benign paroxysmal positional vertigo.
    Acta Otolaryngol. 137: 265-269, 2017.
  • Yonekura S, Okamoto Y, Sakurai D, Sakurai T, Iinuma T, Yamamoto H, Hanazawa T, Horiguchi S, Kurono Y, Honda K, Majima Y, Masuyama K, Takeda N, Fujieda S, Okano M, Ogino S, Okubo K.
    Complementary and alternative medicine for allergic rhinitis in Japan.
    Allergol Int. 66: 425-431, 2017.
  • Kondo E, Jinnouchi O, Nakano S, Ohnishi H, Kawata I, Okamoto H, Takeda N.
    Aural stimulation with capsaicin ointment improved swallowing function in elderly patients with dysphagia: a randomized, placebo-controlled, double-blind, comparative study.
    Clin. Invest. Aging 12: 1921-1928, 2017.
  • Fukushima M, Yokoi K, Iga J, Akahania S, Inohara H, Takeda N.
    Contralateral type of delayed endolymphatic hydrops may consist of two phenotypes based on a magnetic resonance imaging preliminary study.
    Acta Otolaryngol. 137: 1153-1157, 2017.
  • Fukushima M, Kitahara T, Oya R, Akahani S, Inohara H, Naganawa S, TakedaN. Longitudinal up-regulation of endolymphatic hydrops in patients with Meniere's disease during medical treatment.
    Laryngoscope Investig. Otolaryngol. 2: 344-350, 2017.
  • Imai T, Takimoto Y, Takeda N, Okumura T, Inohara H.
    Three-dimensional analysis of linear vestibulo-ocular reflex in humans during eccentric rotation while facing downwards.
    Exp. Brain Res. 235: 2575-2590, 2017.
  • Okumura T, Imai T, Takimoto Y, Takeda N, Kitahara T, Uno A, Kamakura T, Osaki Y, Watanabe Y, Inohara H.
    Assessment of endolymphatic hydrops and otolith function in patients with Ménière's disease.
    Eur Arch Otorhinolaryngol. 274: 1413-1421, 2017.

2016年

  • Kitamura Y, Mizuguchi H, Kitayama M, Okamoto K, Fujii T, Fujioka A, Matsushita T, Mukai T, Kubo Y, Kubo N, Fukui H, Takeda N.
    Irradiation with narrowband-ultraviolet B suppresses phorbol ester-induced up-regulation of H1 receptor mRNA in HeLa cells.
    Acta Otolaryngol. 136: 409-413, 2016.
  • Nakano S, Iwasaki H, Kondo E, Miyazaki K, Shizuku H, Kamimura S, Fukuda J, Kanamura R, Takeda N.
    Efficacy of proton pump inhibitor in combination with rikkunshito in patients complaining of globus pharyngeus.
    J. Med. Invest. 63: 227-229, 2016.
  • Imai T, Takimoto Y, Takeda N, Uno A, Inohara H, Shimada S.
    High-speed video-oculography for measuring three-dimensional rotation vectors of eye movements in mice.
    PLoS One 11: e0152307, 2016.
  • .WadaY, NishiikeS, KitaharaT, YamanakaT, Imai T, Ito T, Sato G, Matsuda K, Kitamura Y, Takeda N.
    Effects of repeated snowboard exercise in virtual reality with time lags of visual scene behind body rotation on head stability and subjective slalom run performance in healthy young subjects.
    Acta Otolaryngol. 136: 1121-1124, 2016
  • Fukushima M, Ito R, Miyaguchi S, Hirai T, Otami Y, Akahani S, Inohara H, Takeda N.
    Preceding profound deafness and co-factors promote development of endolymphatic hydrops in preliminary patients with delayed endolymphatic hydrops.
    Acta Otolaryngol. 136: 1304-1308, 2016
  • Mizuguchi H, Orimoto N, Kadota T, Kominami T, Das A.K. Sawada A, Tamada M, Miyagi K, Adachi T, Matsumoto M, Kosaka T, Kitamura Y, Takeda N, Fukui H.
    Suplatast tosilate alleviates nasal symptoms through the suppression of nuclear factor of activated T-cells-mediated IL-9 gene expression in toluene-2,4-diisocyanate-sensitized rats.
    J. Pharmacol. Sci. 130: 151-158, 2016.
  • Mizuguchi H, Das A.K, Maeyama K, Dev S, Shahriar M, Kitamura Y, Takeda N, Fukui H.
    Antihistamines suppress upregulation of histidine decarboxylase gene expression with potencies different from their binding affinities for histamine H1 receptor in toluene 2,4-diisocyanate-sensitized rats.
    J. Pharmacol. Sci. 130: 212-218, 2016.
  • Shill MC, Mizuguchi H, Karmakar S, Kadota T, Mukherjee PK, Kitamura Y, Kashiwada Y, Nemoto H, Takeda N, Fukui H.
    A novel benzofuran, 4-methoxybenzofuran-5-carboxamide, from Tephrosia purpurea suppressed histamine H1 receptor gene expression through a protein kinase C-δ-dependent signaling pathway.
    Int. Immunopharmacol. 30: 18-26, 2016
  • Tsutsumi R, Goda M, Fujimoto C, Kanno K, Nobe M, Kitamura Y, Abe K, Kawai M, Matsumoto H, Sakai T, Takeda N.
    Effects of chemotherapy on gene expression of lingual taste receptors in patients with head and neck cancer.
    Laryngoscope 126: E103-109, 2016.
  • Hitier M, Sato G, hang YF. Z, Zheng Y, Besnard S, Smith PF, Curthoys IS.
    Anatomy and surgical approach of rat's vestibular sensors and nerves.
    J. Neurosci. Methods. 270: 1-8, 2016.
  • Takimoto Y, Imai T, Okumura T, Takeda N, Uno A, Inohara H.
    Evaluation of otolith function by three-dimensional analysis of vestibulo-ocular reflex during eccentric rotation in humans.
    Neurosci. Res. 111: 34-40, 2016.

2015年

  • Kitamura Y, Nakagawa H, Fujii T, Sakoda T, Enomoto T, Mizuguchi H, Fukui H, Takeda N.
    Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit.
    J. Pharmacol. Sci. 129: 183-187, 2015.
  • Imai T, Matsuda K, Takeda N, Uno A, Kitahara T, Horii A, Nishiike S, Inohara H.
    Light cupula, the pathophysiological basis of persistent geotropic positional nystagmus.
    BMJ Open 5: e006607, 2015.
  • Hitier M, Sato G, Moreau S, Patron V.
    Jugular bulb abnormalities in patients with Meniere's disease using high-resolution computed tomography.
    Eur. Arch. Otorhinolaryngol. 272: 2083-2084, 2015.
  • Yanangawa H, Katashima R, Takeda N.
    Research ethics committees in Japan: A perspective from thirty years of experience at Tokushima University.
    J Med.Invest. 62: 114-118, 2015.
  • Goda M, Jinnouchi O, Takaoka T, Abe K, Tamura K, Nakaya Y, Takechi H, Tangoku A, Takeda N.
    Efficacy of percutaneous endoscopic gastrostomy on unplanned treatment interruption and nutritional status in patients undergoing chemoradiotherapy for advanced head and neck cancer.
    J Med.Invest. 62: 173-176, 2015.
  • Mizuguchi H, Nariai Y, Kato S, NakanoT, KanayamaT, Kashiwada Y, NemotoH, Kawazoe K, Takaishi Y, Kitamura Y, Takeda N, Fukui H.
    Maackiain is a novel antiallergic compound that suppresses transcriptional upregulation of the histamine H1 receptor and interleukin-4 genes.
    PR&P 3: e00166, 2015.
  • Nariai Y, Mizuguchi H, Ogasawara T, Nagai H, Sasaki Y, Okamoto Y, Yoshimura Y, Kitamura Y, Nemoto H, Takeda N , Fukui H.
    Disruption of Heat Shock Protein 90 (Hsp90)-Protein Kinase Cδ (PKCδ) Interaction by (-)-Maackiain Suppresses Histamine H1 Receptor Gene Transcription in HeLa Cells.
    Journal of Biological Chemistry. 290: 27393?2740, 2015.

2014年

  • Kondo E, Jinnouchi O, Ohnishi H, Kawata I, Nakano S, Goda M, Kitamura Y, Abe K, Hoshikawa H, Okamoto H, Takeda N.
    Effects of aural stimulation with capsaicin ointment on swallowing function in elderly patients with non-obstructive dysphagia.
    Clin Interv Aging. 9: 1661-1667, 2014.
  • Zheng Y, Geddes L, Sato G, Stiles L, Darlington CL, Smith PF.
    Galvanic vestibular stimulation impairs cell proliferation and neurogenesis in the rat hippocampus but not spatial memory.
    Hippocampus. 24: 541-52, 2014.
  • Sato G, Sekine K, Matsuda K, Ueeda H, Horii A, Nishiike S, Kitahara T, Uno A, Imai T, Inohara H, Takeda N
    Long-term prognosis of hearing loss in patients with unilateral Meniere's disease
    Acta Otolaryngol. 134: 1005-1010, 2014.

2013年

  • Okazaki S, Nishiike S, Watanabe H, Imai T, Uno A, Kitahara T, Horii A, Kamakura T, Takimoto Y, Takeda N, Inohara H.
    Effects of repeated optic flow stimulation on gait termination in humans.
    Acta Otolaryngol. 133: 246-252, 2013.
  • Iwasaki H, Toda N, Takahashi M, Azuma T, Nakamura K, Takao SI, Harada M, Takeda N.
    Vestibular and cochlear neuritis in patients with Ramsay Hunt syndrome: a Gd-enhanced MRI study.
    Acta Otolaryngol. 133: 373-377, 2013.
  • Bando R, Ikushima H, kwanaka T, Kubo T, Sasaki M, Tominaga M, Kishi T, Furutani S, Kubo A, Tamura K.
    Changes of tumor and nomal structures of the neck during radiation therapy for head and neck cancer requires adaptive strategy.
    J Med Invest. 60: 46-51, 2013.
  • Imai T, Masumura C, Takeda N, Kitahara T, Uno A, Horii A, Nishiike S, Ohta Y, Shingai-Higashi K, Morihana T, Okazaki S, Kamakura T, Takimoto Y, Inohara H.
    Pseudo-anterior canalolithiasis.
    Acta Otolaryngol. 133: 246-252, 2013.
  • Kuroda W, Kitamura Y, Mizuguchi H, Miyamoto Y, Kalubi B, Fukui H, Takeda N.
    Combination of Leukotoriene Receptor Antagonist With Antihistamine Has an Additive Suppressive Effect on the Up-regulation of H1-Receptor mRNA in the Nasal Mucosa of Toluene 2,4-Diisocyanate-Sensitized Rat.
    J Pharmacol Sci. 122: 55-58, 2013.
  • Hattori M, Mizuguchi H, Baba Y, Ono S, Nakano T, Zhang Q, Sasaki Y, Kobayashi M, Kitamura Y, Takeda N, Fukui H.
    Quercetin inhibits transcriptional up-regulation of histamine H1 receptor via suppressing protein kinase C-δ/extracellular signal-regulated kinase/poly(ADP-ribose)polymerase-1 signaling pathway in HeLa cells.
    Int Immunopharmacol. 15: 232-239, 2013.
  • Nishiike S, Okazaki S, Watanabe H, Akizuki H, Imai T, Uno A, Kitahara T, Horii A, Takeda N, Inohara H.
    The effect of visual-vestibulosomatosensory conflict induced by virtual reality on postural stability in humans.
    J. Med. Invest. 60: 236-239, 2013.
  • Nagashima H, Udaka J, Chida I, Shimada A, Kondo E, Takeda N.
    Air-bone gap estimated with multiple auditory steady-state response in young children with otitis media with effusion.
    Auris Nasus Larynx 40: 534-538, 2013.
  • Chida I, Tamura K, Nakagawa S, Ando M, Kuno E, Hoshikawa H, Mori N, Takeda N.
    Clinical outcomes of tracheoesophageal diversion and laryngotracheal separation in neurologically impaired children.
    Auris Nasus Larynx 40: 383-387, 2013.
  • Sato G, Sekine K, Matsuda K, Takeda N, Sekine K, Matsuda K, Takeda N.
    Risk factors for poor outcome of a single Epley maneuver and residual positional vertigo in patients with benign paroxysmal positional vertigo.
    Acta Otolaryngol. 133: 1124-1127, 2013.

2012年

  • Azuma T, Nakamura K, Takahashi M, Ohyama S, Toda N, Iwasaki H, Kalubi B, N. Takeda.
    Mirror biofeedback rehabilitation after administration of single dose of botulinum toxin for treatment of facial synkinesis.
    Otolaryngol. Head Neck Surg. 146: 40-45, 2012.
  • Sarukura N, Takai S, Ikemoto S, Korin T, Ueda Y, Kitamura K, Kalubi B, Yamamoto S, Takeda N.
    Effects of dietary zinc deprivation on zinc concentration and ratio of apo/holo-activities of angiotensin converting enzyme in serum of mice.
    Auris Nasus Larynx 39: 294-297, 2012.
  • Horii A, Nakagawa A, Uno A, Kitahara T, Imai T, Nishiike S, Takeda N, Inohara H.
    Implication of substance P neuronal system in the amygdala as a possible mechanism for hypergravity-induced motion sickness.
    Brain Res, 1435: 91-98, 2012.
  • Higashi-Shingai K, Imai T, Takeda N, Uno A, Nishiike S, Horii A, Kitahara T, Fuse Y, Hashimoto M, Senba O, Suzuki T, Fujita T, Otsuka H, Inohara H.
    3D analysis of spontaneous upbeat nystagmus in a patient with astrocytoma in cerebellum.
    Aurin Nasus Larynx 39: 216-219, 2012.
  • I. Imai, N. Takeda, A. Uno, A. Horii, T Kitahara, S. Nishiike, K. Higashi-SHingai and H. Inohara
    A case with benign paroxysmal positional vertigo showing sequential
    tlanslation of four types of nystagmus.
    Auris Nasus Larynx 39: 544-548, 2012.
  • O. Jinnouchi, T. Kuwahara, S. Ishida, Y.Okano, Y. Kasei, K. Kunitomo and N. Takeda.
    Anti-bacterial and therapeutic effects of modified Burow’s solution on refractory otorrhea.
    Aurin Nasus Larynx 39: 373-377, 2012.
  • Y. Kitamura, H. Mizuguchi, H. Ogishi, W. Kuroda, M. Hattori, H. Fukui and N. Takeda.
    Pre-seasonal prophylactic treatment with antihistamines suppresses IL-5, but not IL-33 mRNA expression in the nasal mucosa of patients with pollinosis.
    Acta Otolaryngol. 132: 434-438, 2012.
  • C. Fujimoto, N, Takeda, A Matsunaga, A Sawada, T. Tanaka, T. Kimoto, W. Shinahara, T. Sawabuchi, M. Yamaguchi, M Hayama, H. Yanagawa Mihiro Yano and H. Kido.
    Induction and preservation of anti-influenza antigen-specific secretary IgA in nasal washes and IgG in serum of adult influenza patients.
    Influenza Other Respi. Viruses 2012, in press.
  • H. Mizuguchi, T. Terao, M. Kitai, M. Ikeda, Y Yoshimura, A,K, Das, Y. Kitamura, N. Takeda and H. Fulkui.
    Involvement of PKC/ERK/ploy(ADP-ribose) polymerase-1 (PARP) signaling pathway in histamine-induced up-regulation of histamine H1 receptor gene expression in HeLa cells.
    J. Biochem., 2012, in press.

2011年

  • Nurul IM, Mizuguchi H, Shahriar M, Venkatesh P, Maeyama K, Mukherjee PK, Hattori M, Choudhuri MS, N Takeda, H Fukui.
    Albizia lebbeck suppresses histamine signaling by the inhibition of histamine H1 receptor and histidine decarboxylase gene transcriptions.
    Int. Immunopharmacol. 11:1766-1772, 2011.
  • T Imai, N Takeda , M Ito , H Inohara.
    Natural course of positional vertigo in patients with apogeotropic variant of horizontal canal benign paroxysmal positional vertigo
    Auris Nasus Larynx 38:2-5, 2011.
  • N Sarukura, M Kogirima, S Takai, Y Kitamura, B Kalubi, S Yamamoto, N Takeda.
    Dietary zinc intake and its effects on zinc nutrition in healthy Japanese living in the central area of Japan
    J. Med. Invest. 58:203-209, 2011.
  • Umehara H, Mizuguchi H, Mizukawa N, Matsumoto M, Takeda N, Senba E Fukui H.
    Deprivation of anticipated food under scheduled feeding induces c-Fos expression in the caudal part of the arcuate nucleus of hypothalamus through histamine H1-receptors in rats: potential involvement of E3 subgroup of histaminergic neurons in tuberomammillary nucleus.
    Brain Res. 1387: 61-70, 2011.
  • H. Mizuguchi, T. Terao, M. Kitai, M. Ikeda, Y Yoshimura, A.K. Das, Y. Kitamura, N. Takeda and H. Fulkui.
    Involvement of protein kinase Cdelta/extracellular signal-regulated kinase/ploy(ADP-ribose) polymerase-1 (PARP-1) signaling pathway in histamine-induced up-regulation of histamine H1 receptor gene expression in HeLa cells.
    J. Biol. Chem. 286: 30542-30551, 2011.

2010年

  • H. Mizuguchi, Y. Kitamura, Y. Kondo, W. Kuroda, H. Yoshida, Y. Miyamoto, M. Hattori,
    H. Fukui, N. Takeda.
    Preseasonal prophylactic treatment with antihistamines suppresses nasal symptoms and expression of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis.
    Meth. Find. Exp. Clin. Pharmacol. 32 : 745-748, 2010.
  • T. Takaoka, N. Sarukura, C. Ueda, Y. Kitamura, B. Kalubi, N. Toda, K. Abe, S. Yamamoto, N. Takeda.
    Effects of zinc supplementation on serum zinc concentration and ratio of apo/holo-activities of angiotensin converting enzyme in patients with taste impairment.
    Auris Nasus Larynx 37 : 190-194, 2010.
  • H. Shojaku, Y. Watanabe, N. Takeda, T. Ikezono, M. Takahashi, A. Kakigi, J. Ito, K. Doi, M. Suzuki, M. Takumida, K. Takahashi, H. Yamashita, I. Koizuka, S. Usami, M. Aoki, H. Naganuma.
    Clinical characteristics of delayed endolymphatic hydrops in Japan: a nationwide survey by the Peripheral Vestibular Disorder Research Committee of Japan.
    Acta Otolaryngol. 130 : 1135-1140, 2010.
  • T. Imai, A. Horii, N. Takeda, T. Kitahara, K. Higashi-Shingai, H. Inohara.
    A case of apogeotropic nystagmus with brainstem lesion: an implication for mechanism of central apogeotropic nystagmus.
    Auris Nasus Larynx 37 : 742-746, 2010.
  • N. Kuroda, DV Kazakov, O. Hes, M. Michal, M. Goda, K. Miyazaki, Y. Hayashi, S. Okamoto, GH Lee.
    Hybrid peripheral nerve sheath tumor of the nasal cavity showing schwannomatous, neurofibromatous, and perineuriomatous areas.
    Med. Mol. Morphol. 43 : 82-85, 2010.
  • H. Umehara, H. Mizuguchi, N. Mizukawa, M. Matsumot, N. Takeda, E. Senba, H. Fukui.
    Innervation of histamine neurons in the caudal part of the arcuate nucleus of hypothalamus and their activation in response to food deprivation under scheduled feeding.
    Meth. Find. Exp. Clin. Pharmacol. 32 : 733-736, 2010.

2009年

  • K. Tamura, M. Kim, K. Abe, N. Toda, O. Jinouchi, B. Kalubi and N. Takeda
    A new video laryngo-pharyngoscope with shape-holding coiled tube and surgical forceps: a preliminary study.
    Auris Nasus Larynx 36: 677-681, 2009.
  • G. Sato, A. Uno, A. Horii, H. Umehara, Y. Kitamura, K. Sekine, K. Tamura, H. Fukui and N. Takeda
    Effects of hypergravity on histamine H1 receptor mRNA expression in hypothalamus and brainstem of rats: implication for development of motion sickness.
    Acta Otolaryngol. 129: 45-51, 2009.
  • C. Fujimoto, H. Kido, T. Sawabuchi, D. Mizuno, M. Hayama, H. Yanagawa and N. Takeda
    Evaluation of nasal IgA secretion in normal subjects by nasal spray and aspiration.
    Auris Nasus Larynx 36: 300-304, 2009.
  • T. Takaoka, N. Sarukura, C. Ueda, Y. Kitamura, B. Kalubi, N. Toda, K. Abe, S. Yamamoto and N. Takeda
    Effects of zinc supplementation on serum zinc concentration and ratio of apo/holo-activities of angiotensin converting enzyme in patients with taste impairment.
    Auris Nasus Larynx 37: 190-194, 2009.
  • T. Imai, N. Takeda, M. Ito, K. Sekine, G. Sato, Y. Midoh, K. Nakamae and T. Kubo
    3D analysis of benign paroxysmal positional nystagmus due to cupulolithiasis in posterior semicircular canal.
    Acta Otolaryngol. 129: 1044-1049, 2009.
  • M. Shahriar, H. Mizuguchi, K. Maeyama, Y. Kitamura, N. Orimoto, S. Horio, H. Umehara, M. Hattori, N. Takeda and H. Fukui
    Suplatast tosilate inhibits histamine signaling by direct and indirect down-regulation of histamine H1 receptor gene expression through suppression of histidine decarboxylase and IL-4 gene transcriptions.
    J. Immunol. 183: 2133-2141, 2009.
  • A.K. Das, H. Mizuguchi, M. Kodama, S. Dev, H. Umehara, Y. Kitamura, C. Matsushita, N. Takeda and H. Fukui
    Sho-seiryu-to suppresses histamine signaling at the transcriptional level in TDI-sensitized nasal allergy model rats.
    Allergol. Int. 58: 81-88, 2009.
  • M. Sakagami, M. Ikeda, H. Tomita, A. Ikui, T. Aiba, N. Takeda, A. Inokuchi, Y. Kurono, M. Nakashima, Y. Sibasaki and O. Yotsuya
    A zinc containing compound, polaprezinc, is effective for patients with taste disorders: randomized, double-blind, placebo-controlled, multi-center study.
    Acta Otolaryngol. 129: 1115-1120, 2009.
  • H. Shojaku, Y. Watanabe, T. Yagi, M. Takahashi, T. Takeda, T. Ikezono, J. Ito, T. Kubo, M. Suzuki, M. Takumida, N. Takeda, N. Furuya, H. Yamashita
    Changes in the characteristics of definite Meniere's disease over time in Japan: a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan.
    Acta Otolaryngol. 129: 155-160, 2009.

2008年

  • H. Shizuku, Y. Hori, T. Uemura, H. Nakagawa, K. Matsuda, B. Kalubi, N. Takeda
    Combination of Bernouilli effect producing maneuver-induced pharyngeal narrowing rate with body mass index as predictive tool for obstructive sleep apnea syndrome.
    Acta Otolaryngol. 128: 569-573, 2008.
  • T. Imai, N. Takeda, G. Sato, K. Sekine, M. Ito, K. Nakamae, T. Kubo
    Changes in slow phase eye velocity and time constant of positional nystagmus at transform from cupulolithiasis to canalolithiasis.
    Acta Otolaryngol. 128: 22-28, 2008
  • T. Imai, N. Takeda, G. Sato, K. Sekine, M. Ito, K. Nakamae, T. Kubo
    Differential diagnosis of true and pseudo-bilateral benign positional nystagmus.
    Acta Otolaryngol. 128: 151-158, 2008
  • S. Ohyama, S. Nishiike, H. Watanabe, K. Matsuoka, N. Takeda
    Effects of optokinetic stimulation induced by virtual reality on locomotion: a preliminary study.
    Acta Otolaryngol. 128: 1211-1214, 2008
  • H. Mizuguchi, M. Hatano, C. Matsushita, H. Umehara, W. Kuroda, Y. Kitamura, N. Takeda, H. Fukui
    Repeated pre-treatment with antihistamines causes transcriptional up-regulations of histamine H(1) receptor and interleukin-4 genes in toluene-2,4-diisocyanate-sensitized rats.
    J. Pharmacol. Sci. 108:480-486, 2008

2007年

  • Das AK, Yoshimura S, Mishima R, Fujimoto K, Mizuguchi H, Dev S, Wakayama Y, Kitamura Y, Horio S, Takeda N, Fukui H
    Stimulation of histamine h(1) receptor up-regulates histamine h(1) receptor itself through activation of receptor gene transcription.
    J Pharmacol Sci. 2007 Apr;103(4):374-82.
  • Ohyama S, Nishiike S, Watanabe H, Matsuoka K, Akizuki H, Takeda N, Harada T.
    Autonomic responses during motion sickness induced by virtual reality.
    Auris Nasus Larynx. 2007 Sep;34(3):303-6.
  • Identification and analysis of the promoter region of the type II transmembrane serine protease polyserase-1 and its transcript variants.
    Biol Chem. 2007 Aug;388(8):853-8.

2006年

  • Ueda C, Takaoka T, Sarukura N, Matsuda K, Kitamura Y, Toda N, Tanaka T, Yamamoto S, Takeda N.
    Zinc nutrition in healthy subjects and patients with taste impairment from the view point of zinc ingestion, serum zinc concentration and angiotensin converting enzyme activity.
    Auris Nasus Larynx. 2006 Mar 8.
  • Imai T, Takeda N, Ito M, Nakamae K, Sakae H, Fujioka H, Kubo T.
    Three-dimensional analysis of benign paroxysmal positional nystagmus in a patient with anterior semicircular canal variant.
    Otol Neurotol. 2006 Apr;27(3):362-6.
  • Imai T, Takeda N, Ito M, Nakamae K, Sakae H, Fujioka H, Matsunaga T, Kubo T.
    Benign paroxysmal positional vertigo due to a simultaneous involvement of both horizontal and posterior semicircular canals.
    Audiol Neurootol. 2006;11(3):198-205.
  • Yohji Hori, Haruhiko Shizuku, Akio Kondo, Hideyuki Nakagawa, Bukasa Kalubi and Noriaki Takeda
    Endoscopic evaluation of dynamic narrowing of the pharynx by the Bernouilli effect producing maneuver in patients with obstructive sleep apnea syndrome.
    Auris Nasus Larynx. 2006 Dec;33(4):429-32.

2005年

  • Imai T, Ito M, Takeda N, Uno A, Matsunaga T, Sekine K, Kubo T.
    Natural course of the remission of vertigo in patients with benign paroxysmal positional vertigo.
    Neurology. 2005 Mar 8;64(5):920-1.
  • Imai T, Sekine K, Hattori K, Takeda N, Koizuka I, Nakamae K, Miura K, Fujioka H, Kubo T.
    Comparing the accuracy of video-oculography and the scleral search coil system in human eye movement analysis.
    Auris Nasus Larynx. 2005 Mar;32(1):3-9.
  • Akizuki H, Uno A, Arai K, Morioka S, Ohyama S, Nishiike S, Tamura K, Takeda N.
    Effects of immersion in virtual reality on postural control.
    Neurosci Lett. 2005 Apr 29;379(1):23-6.
  • Ishimaru N, Arakaki R, Watanabe M, Kobayashi M, Miyazaki K, Hayashi Y.
    Development of autoimmune exocrinopathy resembling Sjogren's syndrome in estrogen-deficient mice of healthy background.
    Am J Pathol. 2003 Oct;163(4):1481-90.
  • N. Toda, K. Nakamura and N. Takeda
    Blink reflex R2 recovery curves in patients with facial palsy within ten days after onset.
    ORL J Otorhinolaryngol Relat Spec. 2005;67(1):16-22.
  • T. Kitahara, N. Takeda, S. Nishiike, S. Okumura and T. Kubo
    Prognosis of inner ear periphery and central vestibular plasticity in sudden deafness with vertigo.
    Ann Otol Rhinol Laryngol. 2005 Oct;114(10):786-91.
  • M. Ando, K. Sawada, H. Sakata-Haga, Y.-G. Jeong, N. Takeda, and Y. Fukui
    Regional difference in corticotropin-releasing factor immunoreactivity in mossy fiber terminals innervating calretinin-immunoreactive unipolar brush cells in vestibulocerebellum of rolling mouse Nagoya.
    Brain Res. 2005 Nov 23;1063(1):96-101.
  • Sekine K, Morita K, Masuda K, Sato G, Rokutan K, Takeda N
    Microarray Analysis of Stress-Related Gene Expression in Patients with Meniere's Disease.
    ORL J Otorhinolaryngol Relat Spec. 2005;67(5):294-9.
  • Ikeda M, Aiba T, Ikui A, Inokuchi A, Kurono Y, Sakagami M, Takeda N, Tomita H.
    Taste disorders: a survey of the examination methods and treatments used in Japan.
    Acta Otolaryngol. 2005 Nov;125(11):1203-10.
  • K. Miyazaki, N. Takeda, N. Ishimaru, F. Omotehara, R. Arakaki and Y Hayashi
    Analysis of in vivo role of alpha-fodrin autoantigen in primary Sjogren's syndrome.
    Am J Pathol. 2005 Oct;167(4):1051-9

2004年

  • Sekine K, Imai T, Nakamae K, Miura K, Fujioka H, Takeda N.
    Dynamics of the vestibulo-ocular reflex in patients with the horizontal semicircular canal variant of benign paroxysmal positional vertigo.
    Acta Otolaryngol. 2004 Jun;124(5):587-94.
  • Horii A, Mitani K, Kitahara T, Uno A, Takeda N, Kubo T.
    Paroxetine, a selective serotonin reuptake inhibitor, reduces depressive symptoms and subjective handicaps in patients with dizziness.
    Otol Neurotol. 2004 Jul;25(4):536-43.
  • Sawada K, Ando M, Sakata-Haga H, Sun XZ, Jeong YG, Hisano S, Takeda N, Fukui Y.
    Abnormal expression of tyrosine hydroxylase not accompanied by phosphorylation at serine 40 in cerebellar Purkinje cells of ataxic mutant mice, rolling mouse Nagoya and dilute-lethal.
    Congenit Anom (Kyoto). 2004 Mar;44(1):46-50.
  • Murata Y, Miyoshi A, Kitamura Y, Takeda N, Fukui H.
    Up-regulation of histamine H(1) receptors in an allergic rat nasal mucosa model.
    Inflamm Res. 2004 Mar;53 Suppl 1:S11-2.
  • Kitamura Y, Miyoshi A, Murata Y, Maeyama K, Takeda N, Fukui H.
    Increase in the level of histidine decarboxylase mRNA expression in nasal mucosa of rats sensitized by toluene diisocyanate.
    Inflamm Res. 2004 Mar;53 Suppl 1:S13-4.
  • Horii A, Mitani K, Kitahara T, Uno A, Takeda N, Kubo T.
    Paroxetine, a selective serotonin reuptake inhibitor, reduces depressive symptoms and subjective handicaps in patients with dizziness.
    Otol Neurotol. 2004 Jul;25(4):536-43.
  • Sekine K, Imai T, Morita M, Nakamae K, Miura K, Fujioka H, Kubo T, Tamura K, Takeda N.
    Vertical canal function in normal subjects and patients with benign paroxysmal positional vertigo.
    Acta Otolaryngol. 2004 Nov;124(9):1046-52.
  • Kitamura Y, Miyoshi A, Murata Y, Kalubi B, Fukui H, Takeda N.
    Effect of glucocorticoid on upregulation of histamine H1 receptor mRNA in nasal mucosa of rats sensitized by exposure to toluene diisocyanate.
    Acta Otolaryngol. 2004 Nov;124(9):1053-8.
  • Takeda N, Takaoka T, Ueda C, Toda N, Kalubi B, Yamamoto S.
    Zinc deficiency in patients with idiopathic taste impairment with regard to angiotensin converting enzyme activity.
    Auris Nasus Larynx. 2004 Dec;31(4):425-8.

2003年

  • Nakagawa A, Uno A, Horii A, Kitahara T, Kawamoto M, Uno Y, Fukushima M, Nishiike S, Takeda N, Kubo T.
    Fos induction in the amygdala by vestibular information during hypergravity stimulation.
    Brain Res. 2003 Oct 3;986(1-2):114-23.
  • Morita M, Imai T, Kazunori S, Takeda N, Koizuka I, Uno A, Kitahara T, Kubo T.
    A new rotational test for vertical semicircular canal function.
    Auris Nasus Larynx. 2003 Aug;30(3):233-7.
  • Kitahara T, Kondoh K, Morihana T, Okumura S, Horii A, Takeda N, Kubo T.
    Steroid effects on vestibular compensation in human.
    Neurol Res. 2003 Apr;25(3):287-91.
  • Nakamura K, Toda N, Sakamaki K, Kashima K, Takeda N.
    Biofeedback rehabilitation for prevention of synkinesis after facial palsy.
    Otolaryngol Head Neck Surg. 2003 Apr;128(4):539-43.
  • Akiduki H, Nishiike S, Watanabe H, Matsuoka K, Kubo T, Takeda N.
    Visual-vestibular conflict induced by virtual reality in humans.
    Neurosci Lett. 2003 Apr 17;340(3):197-200.

2002年

  • Imai T, Takeda N, Uno A, Morita M, Koizuka I, Kubo T.
    Three-dimensional eye rotation axis analysis of benign paroxysmal positioning nystagmus.
    ORL J Otorhinolaryngol Relat Spec. 2002 Nov-Dec;64(6):417-23.
  • Rudd JA, Yamamoto K, Yamatodani A, Takeda N.
    Differential action of ondansetron and dexamethasone to modify cisplatin-induced acute and delayed kaolin consumption ("pica") in rats.
    Eur J Pharmacol. 2002 Nov 1;454(1):47-52.
  • Kitahara T, Nakagawa A, Fukushima M, Horii A, Takeda N, Kubo T.
    Changes in fos expression in the rat brainstem after bilateral labyrinthectomy.
    Acta Otolaryngol. 2002 Sep;122(6):620-6.
  • Nishiike S, Nakagawa S, Nakagawa A, Uno A, Tonoike M, Takeda N, Kubo T.
    Magnetic cortical responses evoked by visual linear forward acceleration.
    Neuroreport. 2002 Oct 7;13(14):1805-8.

2001年

  • Sawada K, Sakata-Haga H, Ando M, Takeda N, Fukui Y.
    An increased expression of Ca(2+) channel alpha(1A) subunit immunoreactivity in deep cerebellar neurons of rolling mouse Nagoya.
    Neurosci Lett. 2001 Dec18;316(2):87-90.
  • Nishiike S, Takeda N, Kubo T, Nakamura S.
    Noradrenergic pathways involved in the development of vertigo and dizziness--a review.
    Acta Otolaryngol Suppl. 2001;545:61-4. Review.
  • Nishiike S, Nakagawa S, Tonoike M, Takeda N, Kubo T.
    Information processing of visually-induced apparent self motion in the cortex of humans: analysis with magnetoencephalography.
    Acta Otolaryngol Suppl. 2001;545:113-5.
  • Kitahara T, Fukushima M, Takeda N, Saika T, Uno A, Kubo T.
    Role of cholinergic mossy fibers in vestibular nuclei in the development of vestibular compensation.
    Acta Otolaryngol Suppl. 2001;545:101-4.
  • Takeda N, Morita M, Horii A, Nishiike S, Kitahara T, Uno A.
    Neural mechanisms of motion sickness.
    J Med Invest. 2001 Feb;48(1-2):44-59. Review.
  • Nishiike S, Uno A, Kubo T, Yamatodani A, Takeda N, Nakamura S.
    Effect of AF64A, a cholinergic neurotoxin, on footshock stimulation-induced locus coeruleus excitation in rats.
    Neurosci Lett. 2001 Apr 13;302(1):33-6.
  • Fukushima M, Kitahara T, Takeda N, Saika T, Uno A, Kubo T.
    Role of cholinergic mossy fibers in medial vestibular and prepositus hypoglossal nuclei in vestibular compensation.
    Neuroscience. 2001;102(1):159-66.
  • Kitahara T, Takeda N, Mishiro Y, Saika T, Fukushima M, Okumura S, Kubo T.
    Effects of exposing the opened endolymphatic sac to large doses of steroids to treat intractable Meniere's disease.
    Ann Otol Rhinol Laryngol. 2001 Feb;110(2):109-12

2000年

  • Kitahara T, Fukushima M, Takeda N, Saika T, Kubo T.
    Effects of pre-flocculectomy on Fos expression and NMDA receptor-mediated neural circuits in the central vestibular system after unilateral labyrinthectomy.
    Acta Otolaryngol. 2000 Oct;120(7):866-71.
  • Uno A, Takeda N, Horii A, Sakata Y, Yamatodani A, Kubo T.
    Effects of amygdala or hippocampus lesion on hypergravity-induced motion sickness in rats.
    Acta Otolaryngol. 2000 Oct;120(7):860-5.
  • Nishiike S, Takeda N, Uno A, Kubo T, Yamatodani A, Nakamura S.
    Cholinergic influence on vestibular stimulation-induced locus coeruleus inhibition in rats.
    Acta Otolaryngol. 2000 Mar;120(3):404-9.
  • Uno A, Takeda N, Kitahara T, Sakata Y, Yamatodani A, Kubo T.
    Effects of vestibular cerebellum lesion on motion sickness in rats.
    Acta Otolaryngol. 2000 Mar;120(3):386-9.
  • Mishiro Y, Sakagami M, Okumura S, Takeda N, Kubo T.
    Postoperative results for cholesteatoma in children.
    Auris Nasus Larynx. 2000 Jul;27(3):223-6.
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